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Study
Cell Signaling Part 2
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Any one ligand for nuclear receptor
Steroid hormones, Thyroid hormones, Retinoid etc
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How many times polypeptide of GPCR intervene plasma membrane ?
7
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Which two sub-units of G protein are linked to plasma membrane?
α and γ.
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What is the total number of subunits present on cAMP dependent protein kinases (PKA)?
4
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Which protein binds PKA to the cytoskeleton ?
A kinase anchoring protein (AKAP)
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Full form of GPCR
G proteinn coupled receptor
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What is the function of GTPase-activating proteins?
(GAPs) drive the proteins into an “off” state by increasing the rate of hydrolysis of bound GTP.
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What is the function of loops of GPCR on cytosolic side of plasma membrane?
Binding site for G protein/Arrestin
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Binding of ________ α subunit dissociates from trimmer of G protein
GTP
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Give an example of enzyme that brings about phosphorylation
Kinases
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