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Central dogma

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  • A particular triplet of bases in the template strand of DNA is 5ʹ AGT 3ʹ. The corresponding anticodon for the tRNA transcribed is
    5ʹ AGU 3ʹ
  • The coding sequences on mRNA is called
    Exons
  • What amino acid sequence will be generated, based on the following mRNA codon sequence? 5ʹ AUG-UCU-UCG-UUA-UCC-UUG 3ʹ?
    met-ser-ser-leu-ser-leu
  • Using RNA as a template for protein synthesis instead of translating proteins directly from the DNA is advantageous for the cell because
    DNA can't leave the nucleus
  • How does the mRNA leave the nucleus ?
    nuclear pore
  • processing of the pre-mRNA includes adding a protective cap on the
    5' end
  • A particular triplet of bases in the coding sequence of DNA is AAA. The anticodon on the tRNA that binds the mRNA codon is
    UUU
  • an enzyme that unwind and separate the two strands and binds to a specific section where an mRNA ( messenger RNA ) will be synthesized
    RNA polymerase
  • involves the synthesis of mRNA from DNA
    Transcription
  • How many nucleotide does the tRNA carries ?
    3
  • What is the most abundant type of RNA?
    rRNA
  • Three main process of the central dogma
    Transcription , RNA Processing , Translation
  • What is the function of a poly (A) signal sequence?
    Stabilizing the mRNA
  • Preparing the mRNA before leaving the nucleus
    RNA processing
  • What are polyribosomes?
    groups of ribosomes reading a single mRNA simultaneously
  • What kind of RNA that makes the ribosome ?
    rRNA
  • it carries a specific amino acid , what is it ?
    tRNA
  • .
    D
  • A transcription unit that is 8,000 nucleotides long may use 1,200 nucleotides to make a protein consisting of approximately 400 amino acids. This is best explained by the fact that
    There are more introns than exons
  • Where does translation process takes place ?
    in Cytoplasm
  • A transfer RNA (#1) attached to the amino acid lysine enters the ribosome. The lysine binds to the growing polypeptide on the other tRNA (#2) in the ribosome already.
    E site
  • There are 61 mRNA codons that specify an amino acid, but only 45 tRNAs. This is best explained by the fact that
    Amino acid could be expressed by more than one codon
  • What is the function of poly-A tail on 3' end of the mRNA
    Stabilizing the mRNA
  • A changing which parts of RNA is likely to be most damaging to a cell?
    Exons
  • s an explanation of the flow of genetic information within a biological system. It is often stated as "DNA makes RNA, and RNA makes protein"
    Central dogma