SIGS Unit 8 | Baamboozle - Baamboozle | The Most Fun Classroom Games!

English 25 Public

SIGS class review

Study Slideshow

Discuss mechanisms underlying neuronal injury after an ischemic event

neurons need O2 and glucose (no glycogen storage)

15

Discuss the risks and benefits of administering tPA

Risks: cause a bleed, exacerbate a bleed. Benefits: save the penumbra!

15

Differentiate expressive, conductive, and receptive aphagia

Expressive: Broca's motor non-fluent. Conductive: aka global. Arcuate fasiculus connects. Receptive: Wernike, understanding "word salad"

15

Explain how peginterferon beta-1 therapy is utlized in MS

Interferon beta1 is a polypeptide that binds to immune cells to ↓ antigen presentation and t-cell proliferation. PEG extends the half-life of the drug.

15

Describe Lhermitte's phenomenon

It's an uncomfortable electrical sensation running through the back and limbs that is elicited by flexing the head. The pain can ascend or descend. (MS)

15

Draw out the basal ganglia pathway including major structures, neurotransmitters, and overall function (sorry guys!)

motor cortex, striatum (CN+P), GPi, substantia niagra, thalamus, GPe, subthalamic nucleus

25

Overall, parkinson Dz is a ____ of dopamine and huntington is a _____ of dopamine

Parkinson = dopamine deficiency. Huntington = dopamine excess

5

Modifiable risk factors in alzheimer Dz

Diabetes, obesity, dyslipidemia, HTN, artherosclerosis, cerebrovascular Dz

15

What is the suspected pathophysiology of Meniere Dz?

impaired absorption or overactive production of endolymph (viral, autoimmune, allergy) → LOSS of vestibular and cochlear input →peripheral vertigo

15

How can one distinguish between central and peripheral vertigo?

HINTS exam (head impulse test, nystagmus, test of skew)

15

Justify why a low salt diet and/or HCTZ are effective therapies for Meniere Dz

Osmotically reduce the pressure of the endolymph

15

Discuss the kindling theory of seizure control

Seizures are the path to epilepsy. Little seizures lead to big seizures, big seizures lead to epilepsy - Yoda or something

15

What is the inheritence pattern of tuberous sclerosis?

autosomal dominant

15

Outline the aura phase of migraine

More tired than usual, excessive yawning, scotoma, photophobia, phonophobia, n/v

15

Amitriptyline is often used off-label for migraine. What is its class?

tricyclic antidepressent (blocks NE and 5HT reputake)

5

What are the components of a mental status exam?

1) Appearance/behavior 2) Speech 3) Mood/affect 3) Thoughts/perceptions 4)judgement/insight 5) cognition (attention, memory, orientation)

15