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Chapter 15- The Chromosomal Basis of Inheritance

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    The Chromosomal Basis of Inheritance
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  • What is the chromosome theory of inheritance?
    Mendelian genes have specific loci (positions) on chromosomes. Chromosomes undergo segregation and independent assortment
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  • Explain the wild type phentoype.
    The phenotype for a character most commonly observed in natural populations.
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  • Explain mutant phenotypes in a population.
    Traits that are alternatives to the wild type suggesting mutations in the alleles over time.
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  • Sex-linked gene
    A gene located on either sex chromosome.
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  • Genes found of the X chromosome.
    X-linked genes
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  • Give an example of an X-linked gene.
    Color blindness, Duchenne muscular dystrophy, Hemophilia
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  • What is a Barr body?
    The inactive X in each cell of a female condenses into a Barr body.
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  • X-linked recessive disorders are much more common in ______ than in _______.
    males, females
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  • In mammalian females, one of the two X chromosomes in each cell is randomly ____________during embryonic development
    inactivated
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  • Each chromosome has______________ or ___________ of genes (except the Y chromosome)
    hundreds or thousands
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  • Genes located on the same chromosome that tend to be inherited together are called ____________________
    Linked Genes
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  • Offspring with nonparental phenotypes (new combinations of traits) are called
    recombinant types, or recombinants
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  • A______ frequency of recombination is observed for any two genes on different chromosomes
    50%
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  • Genes that are far apart on the same chromosome can have a recombination frequency near ____
    50%
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  • In ____________________, pairs of homologous chromosomes do not separate normally during meiosis As a result, one gamete receives two of the same type of chromosome, and another gamete receives no copy
    nondisjunction
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  • _______________ results from the fertilization of gametes in which nondisjunction occurred. Offspring with this condition have an abnormal number of a particular chromosome
    Aneuploidy
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