What is the most distinguished clinical feature you would see on a patient with FH?
Xanthomas
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10
In reference to anabolic and catabolic, what is Glycogenesis? What is Glycogenolysis?
Glycogenesis - anabolic (create glycogen to be stored); Glycogenolysis- catabolic (break down glycogen to useable glucose)
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10
Explain the role of parvovirus B19 in the development of acute anemia (aplastic) crisis with chronic spherocytosis
Parvovirus infects and destroys RBC progenitors in the bone marrow, can halt production of RBCs for 1-2 weeks until immune system controls the infection
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why do we treat sickle cell disease with Hydroxyurea?
increases fetal hemoglobin to retard gelation and sickling of RBCs