Discuss the name, MOA, indications of any thrombolytic drug
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15
Name one possible gain-of-function mutation for developing cutaneous melanoma
BRAF, RAS, cKIT, MEK
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15
Due to a positive family history for anemia and an elongated PTT, you suspect your patient has von Willebrand factor deficiency. What is the appropriate treatment?
Desmopressin
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15
What is one possible etiology of a thrombotic microangiopathy?
ADAMTS13 mutation, Toxins from certain bacteria
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15
Name one possible loss-of-function mutation in the pathogenesis of cutaneous melanoma
CDK4, PTEN, Neurofibromin 1, CDKN2A
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seesaw
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gift
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lifesaver
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15
What is the standard treatment for hypercholesterolemia?
HMG CoA reductase inhibitor (aka statin)
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15
Discuss the name, MOA, indications of any chemotherapeutic drug
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15
What happens to the LDL receptor gene in familial hypercholesterolemia?
LDL receptor gene normally negative feedback. Loss of function leads to loss of inhibition.